The bad to good cholesterol ratios, i.e., LDL HDL ratios are signficant when it comes to reversing atherosclerosis, or hardening of the arteries, caused by deposition of cholesterol plaque.  Keeping our blood vessels free and clear of depositions is tantamount to good health in our later years.  The flexibility as well as ability to keep blood pressure down keeps heart attacks and strokes down.

New research shows that increasing the good or HDL cholesterol as high as possible via a number of important healthy lifestyle tactics plays a huge role in clearing out the arteries.  Signficantly lower mortality rates are achieved than simply by lowering LDL cholesterol alone.  The HDL cholesterol is the body’s scavanger, cleaning up the oxidized and deposited LDL cholesterol in blood vessels.  The more of this compound available, the more efficient this scavanging activity appears to be.

Kinemed just received an award from NIH to advance their novel ApoA-I mimetic lead compound for the treatment of atherosclerosis, which serves to raise HDL levels.  Their FX-5A has such strong potential it is a small synthetic peptide optimized to help the body produce its own cholesterol rather than using a synthetic form of HDL as some other therapies are attempting.

In the meantime, this important focus on HDL points out the importance of using natural therapies that help improve HDL levels in the blood.  These activities include exercise (even just walking), lose fat, stop smoking, cut out trans fat, increase monounsaturated fats such as olive oil and avocado, increase soluble fiber such as oats and apples, increase omega-3 intake such as krill or codliver oil, and niacin supplementation.  All these are discussed in depth in my book “Get Rid of Bad Cholesterol“.

Optimal levels of “good” or HDL cholesterol is over 60 mg/dL while optimal levels of “bad” or LDL cholesterol is below 100 mg/dL.

Current low-density lipoprotein, “LDL” cholesterol, lowering therapies are effective to reduce the risk of coronary events by only 30%, whereas studies suggest that for any given level of LDL-cholesterol, cardiovascular risk may be further reduced by an increase in HDL particle levels….More at Novel Atherosclerosis-Reversing, Heart Disease Therapy Wins NIH Clinical

So you can see, more important than overall cholesterol numbers is the bad to good cholesterol ratio, since these LDL HDL ratios are significant when it comes to reversing atherosclerosis.  What could be better than that, setting our time clocks backwards?